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A near-autonomous AI chemist improves a challenging reaction in medicinal chemistry

June 17, 2026

OpenAI and Molecule.one reported that a near-autonomous AI chemist using GPT-5.4 improved a challenging medicinal-chemistry reaction. The result suggests large models can do more than propose molecules, potentially accelerating optimization of real drug-making steps.

OpenAI and Molecule.one show how a near-autonomous AI chemist using GPT-5.4 improved a key drug-making reaction, advancing medicinal chemistry research.

Source: openai.com

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